Endocrine Abstracts

Background and aims: There are growing evidence supporting the deleterious effect of type 2 diabetes (T2D) on respiratory function and sleep breathing disorders. However, there is no information about the characteristics of lung function in the prediabetes stage.Methods: We assessed pulmonary function in 3,455 non-diabetic subjects, aged between 45 and 70 years, without vascular disease nor chronic pulmonary obstructive disease from the cross-sectional s...

Results: Main clinical, analytical and polygraphic data: 58.1±6.4 years, body mass index 32.4±5.4 kg/m2, 70.4% female, HbA1c 8.0±1.9%, AIH 27.4 events/hour (in the range of severe sleep apnea and hypoapnea index), and CT90% 32.9%. Nocturnal concentration of urine total metanephrines were higher than diurnal levels (226±12 vs 98±13 μg/l; P=0.085). In addition, its nocturnal concentration was significantly associated, in a positi...

Introduction: Obesity and its comorbidities, specially type 2 diabetes (T2D), are a major public health problem. The disappointing result of dietary treatment and the scarce of drugs have led to increased bariatric surgery (BS) as the most efficient therapeutic option. However, not all obese patients with T2D who undergo BS achieve diabetes remission.Objective: To develop a genetic scoring system for predicting T2D remission following BS. 2) To compare o...